We can learn about risks of disease by asking women what diseases have run in their families. This questionnaire asks you about several diseases that may occur in more than one member of a family. For all of these questions, please think about full-blooded relatives only. Do not think about half-sisters or half-brothers, or relatives who are related to you by marriage or adoption. Full-blooded sisters and brothers are those who had the same two parents as you. If you are adopted or are not sure about some relatives' health history, please include any family history that you know about. 1. Have you ever had any full-blooded sisters who reached adulthood (age 21)? yesnodon't know 1.1 How many sisters? Choose One12345678910+ 2. Have you ever had any full-blooded brothers who reached adulthood (age 21)? yesnodon't know 2.1 How many brothers? Choose One12345678910+ 3. Have you ever had any daughters who reached adulthood (age 21)? yesnodon't know 3.1 How many daughters? Choose One12345678910+ 4. Have you ever had any sons who reached adulthood (age 21)? yesnodon't know 4.1 How many sons? Choose One12345678910+ The next two questions are about your natural (not adoptive) mother and father. 5. Is your natural mother still alive? yesnodon't know 5.1 How old was she when she died? (Please guess as closely as you can.) Choose One<4950-5960-6970-7980-8990-9999+ 5.2 How old is she now? (Please guess as closely as you can.) Choose One<4950-5960-6970-7980-8990-9999+ 6. Is your natural father still alive? yesnodon't know 6.1 How old was he when he died? (Please guess as closely as you can.) Choose One<4950-5960-6970-7980-8990-9999+ 6.2 How old is he now? (Please guess as closely as you can.) Choose One<4950-5960-6970-7980-8990-9999+ 7. Did your mother, father, full-blooded sisters, full-blooded brothers, daughters, or sons ever have sugar diabetes or high blood sugar that first appeared as an adult? yesnodon't know 7.1 How many of these relatives had diabetes? Choose One1234+ 8. Did your mother, father, full-blooded sisters, full-blooded brothers, daughters, or sons ever have a heart attack or myocardial infarction? No (Skip to Question 9)Don't know (Skip to Question 9)Yes Please answer the following questions for each of your relatives. If you do not have a full-blooded sister, full-blooded brother, daughter, or son, leave the bubble blank. Age of First Heart Attack < 55 55 - 59 60 - 64 65+ Don't Know Mother Father Sister Sister Sister Brother Brother Brother Daughter Daughter Son Son 9. Did your mother, father, full-blooded sisters, full-blooded brothers, daughters, or sons ever have a stroke? yesnodon't know 9.1 How many of these relatives had a stroke? Choose One1234+ These next questions are about cancers your relatives may have had. For each question, mark "Yes" only if it describes the area where the relative's cancer started. Often cancers will start in one place and then spread. We are interested in where the cancer started. Female relatives 10. Did any of your female relatives ever have cancer? For female relatives, please answer about your mother, full-blooded sisters, daughters, and grandmothers. Do not include aunts, cousins, and nieces.) No (Skip to Question 16)Don't know (Skip to Question 16)Yes 11. Did your mother, full-blooded sisters, daughters, or grandmothers ever have breast cancer? No (Skip to Question 12)Don't know (Skip to Question 12)Yes 11.1 Please answer the following questions for each of your female relatives who had breast cancer. If you do not have a full-blooded sister or daughter, leave the spaces blank. Please note that the age category is different than for the question about heart attacks in relatives. Age of Detection of Breast Cancer < 45 45+ Don't Know Age Mother Sister Sister Sister Daughter Daughter Daughter Maternal Grandmother (Mother's Mother) Paternal Grandmother (Father's Mother) 12. Did your mother, full-blooded sisters, daughters, or grandmothers ever have cancer of the colon, rectum, intestine, or bowel? No (Skip to Question 13)Don't know (Skip to Question 13)Yes 12.1 Please answer the following questions for each of your female relatives who had colon, rectum, intestine, or bowel cancer. If you do not have a full-blooded sister or daughter, leave the spaces blank. Age of Detection of Colon, Rectum, Intestinal Cancer < 45 45+ Don't Know Age Mother Sister Sister Sister Daughter Daughter Daughter Maternal Grandmother (Mother's Mother) Paternal Grandmother (Father's Mother) 13. Did your mother, full-blooded sisters, or daughters ever have cancer of the cervix (opening to the womb)? yesnodon't know 13.1 How many of these relatives had cancer of the cervix? Choose One1234+ 14. Did your mother, full-blooded sisters, or daughters ever have cancer of the uterus, womb, or endometrium (lining of the womb)? yesnodon't know 14.1 How many of these relatives had cancer of the uterus, womb, or endometrium? Choose One1234+ 15. Did your mother, full-blooded sisters, or daughters ever have cancer of the ovaries? yesnodon't know 15.1 How many of these relatives had cancer of the ovaries? Choose One1234+ Male relatives 16. Did any of your male relatives ever have cancer? (For male relatives, please answer about your father, full-blooded brothers, sons, and grandfathers. Do not include uncles, cousins, and nephews.) No (Skip to Question 19)Don't know (Skip to Question 19)Yes 17. Did your father, full-blooded brothers, or sons ever have cancer of the colon, rectum, intestine, or bowel? No (Skip to Question 18)Don't know (Skip to Question 18)Yes 17.1 Please answer the following questions for each of your male relatives who had colon, rectum, intestine, or bowel cancer. If you do not have a full-blooded brother or son, leave those bubbles blank. Age of Detection of Colon, Rectum, Intestinal Cancer < 45 45+ Don't Know Age Father Brother Brother Brother Son Son Son Maternal Grandfather (Mother's Father) Paternal Grandfather (Father's Father) 18. Did your father, full-blooded brothers, or sons ever have cancer of the prostate (male gland)? yesnodon't know 18.1 How many of these relatives had cancer of the prostate? Choose One1234+ Finally we want to ask some questions about your parent's bones. 19. Did your mother ever break or fracture a bone after she was 40 years old? No (Skip to Question 20)Don't know (Skip to Question 20)Yes 19.1 Please answer the following questions for each of the bones listed below. If she broke the bone more than once, mark her age when it was first broken. Age of First Broken Bone 40 - 55 55+ Don't Know Age a) Hip b) Spine (Back/Vertebra) c) Upper Arm (humerus) d) Lower arm or wrist e) Other (specify): 20. Did your father ever break or fracture a bone after he was 40 years old? No (Skip to Question 21)Don't know (Skip to Question 21)Yes 20.1 Please answer the following questions for each of the bones listed below. If he broke the bone more than once, mark his age when it was first broken. Age of First Broken Bone 40 - 55 55+ Don't Know Age a) Hip b) Spine (Back/Vertebra) c) Upper Arm (humerus) d) Lower arm or wrist e) Other (specify): 21. Other illnesses. Please answer the following questions for all full-blooded family members that experienced the following medical conditions. If NONE of your blood relatives have experienced the medical conditions listed, leave the bubbles blank. 21a. Heart problems other than heart attack: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21b. High blood pressure: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21c. Sudden, unexplained death: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21d. High Cholesterol: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21e. Diabetes: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21f. Osteoporosis: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21g. Obesity: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle 21h. Thyroid disease: MotherFatherSisterBrother DaughterSonPaternal GrandmotherPaternal Grandfather Maternal GrandmotherMaternal GrandfatherAuntUncle
Female relatives