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Current Clinical Research: Opportunities to Participate


A major focus of The Stroke Center – Dallas is clinical research. We are recruiting subjects for an ongoing clinical trial of aphasia recovery in collaboration with investigators from The University of Texas Southwestern Medical Center, Dallas. All research activities are carried out on-site at The Stroke Center – Dallas in the T. Boone Pickens Institute of Health Sciences, 5500 Southwestern Medical Avenue, Dallas, TX.

We are Looking for Qualified Participants

Recruitment is underway for a study exploring the use of non-invasive brain stimulation (transcranial direct current stimulation-tDCS) paired with impairment level language therapy to facilitate recovery from aphasia. Participants receive 36 hours of language therapy delivered 1.5 hours per day four days per week for six weeks. Follow-up assessments continue four weeks after the study ends.

Transcranial Direct Current Stimulation (tDCS) in the Treatment of Aphasia:  A Pilot Study

The long term goal of this research is to determine if non-invasive brain stimulation will facilitate recovery from behavioral deficits subsequent to stroke.  The purpose of this pilot study is to explore the efficacy of tDCS paired with 36 hours of language therapy to accelerate recovery from aphasia across a seven-week treatment period.  Participants will receive on a random basis six weeks of real or sham tDCS, paired with language treatment 1.5 hours per day for four days per week. The research team is led by Dr. Delaina Walker-Batson of Texas Woman’s University and Dr. Mark Johnson of The University of Texas Southwestern Medical Center, Dallas.  This study is available at no charge to persons who qualify.  Number of subjects:  16.  Time period:  2 years.

Eligibility Criteria for Transcranial Direct Current Stimulation (tDCS) in the Treatment of Aphasia

Inclusion criteria

  • Single left occlusive cerebral lesion verified by CT or MRI 
  • 30 days post-stroke 
  • 18 - 80 years of age 

Exclusion criteria

  • Brainstem stroke
  • Bilateral involvement
  • Terminal illness/multiple medical problems/atrial fibulation 
  • Prior cerebral infarcts with residual deficits
  • History of head injury with loss of consciousness
  • Neurological condition other than stroke - no seizure activity for the past 12 months
  • History of psychiatric illness requiring hospitalization
  • History of alcohol or drug dependence (required treatment) 
  • Inability to fluently read, write or speak English prior to stroke as all speech-language assessments are standardized only in English
  • Pregnancy
  • Speech apraxia so severe that participant cannot produce a two word utterance
  • Prescribed alpha-adrenergic antagonists or agonists, monoamine oxidase inhibitors, benzodiazepines, scopolamine, haloperidol or Inderal and there is no alternative
  • Currently prescribed dextro-amphetamine sulfate, Ritalin or Adderall

If interested please contact:

The Stroke Center-Dallas
Carol Pickle, Secretary
Phone: 214-689-6592
FAX: 214-689-6614


page last updated 1/11/2016 10:18 AM